San Francisco 49ers head coach Kyle Shanahan told reporters that he would be surprised if star running back Christian ...

Following the significant losses of players due to injury and illness, including Brandon Aiyuk, San Francisco 49ers head ...

San Francisco 49ers head coach Kyle Shanahan brushed aside rumors that there is bad blood with Brock Purdy after reports that ...

The news around wide receiver Brandon Aiyuk's season-ending knee injury during the San Francisco 49ers' 28-18 loss to the ...

And yet Kyle Shanahan treated it like he treats all games: He played not to lose. So the 49ers lost.

If you, as most of us have, have been watching for long enough, you've seen this movie before. A 49ers team coming off a soul ...

Finally, it appears that the 49ers have some received some good news from an injury standpoint. On Monday, a day after his ...

Amid increasing chatter that 49ers running back Christian McCaffrey might make his regular-season debut on Sunday night ...

The 49ers allowed the Chiefs to rush for 184 yards on 39 attempts, an average of 4.7 yards per carry. They held Patrick ...

San Francisco 49ers head coach Kyle Shanahan and quarterback Brock Purdy had a long locker room discussion after Sunday's ...

San Francisco 49ers wide receiver Deebo Samuel is dealing with a "pneumonia-like" illness and has been hospitalized due to the fluid in his lungs, head coach Kyle Shanahan announced Monday. Shanahan ...