While the status of quarterback Brock Purdy has dominated headlines, injuries to tackle Trent Williams and defensive end Nick ...

Jaire Alexander, Edgerrin Cooper, Brock Purdy and Nick Bosa were all ruled out Friday; 49ers LT Trent Williams joins them on ...

The San Francisco 49ers will be without their starting quarterback and their best defensive player when they visit the Green ...

The San Francisco 49ers will be missing two of their best players in their must-win matchup against the Green Bay Packers ...

The 49ers will start Brandon Allen at quarterback against the Packers in place of an injured Brock Purdy. Defensive end Nick ...

Big news and not good news out of the Bay Area on Friday. The 5-5 San Francisco 49ers will be in Green Bay on Sunday to play ...

The 49ers have ruled out quarterback Brock Purdy for Sunday’s game against the Packers. It appeared to be trending that way ...

San Francisco 49ers quarterback Brock Purdy will miss Sunday's game against the Green Bay Packers with a sore throwing ...

Nick Bosa’s injury definitely hurt the 49ers in loss to Seahawks and there’s concern he could miss additional time.

The 49ers have allowed 222 points, or 22.2 points per game, tied for 16th. Last year, the defense allowed 298 points, or 17.5 ...

San Francisco 49ers quarterback Brock Purdy will not play Sunday and head coach Kyle Shanahan said the lingering discomfort ...

Brandon Allen will start in place of an injured Brock Purdy when the 49ers (5-5) also have to play without Nick Bosa on ...