综合研究结果和讨论部分，这项研究意义重大。它首次深入揭示了 LONP1 在前列腺癌中的重要作用和分子机制。LONP1 通过两种不同的机制介导了从氧化磷酸化到糖酵解的代谢转换，一方面降解 MPC1，抑制丙酮酸进入线粒体，另一方面下调线粒体呼吸链复合物 I 的活性，最终促进了前列腺癌细胞的侵袭和转移。这一发现为前列腺癌的治疗开辟了新的方向，比如可以针对 LONP1 ...

A new report shows while cancer death rates among Black people are declining, they remain higher than other racial and ethnic ...

Thousands of men are to be checked for prostate cancer in one of the first large-scale European trials of smart screening. The pilot study, starting next week in Ireland, will combine a blood test ...

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Prostate cancer kills twice as many Black men as white men in the U.S. Beyoncé's father has signed onto a new $20 million ...

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New research maps the global burden of male cancers from 1990 to 2040, showing how aging, lifestyle, and healthcare access ...

The PORTOS assay could indicate when or when not to offer dose-escalated radiation for localized prostate cancer.

Prostate cancer runs in Dean's family, and screening for it every year made it relatively straightforward to address. Now, he ...

The pharma giant hosted its ninth annual Blue Jacket Fashion Show in collaboration with designer Frederick Anderson in New ...

Alarming Rise in Rates of Advanced Prostate Cancer in California Feb. 3, 2025 — The incidence of advanced prostate cancer in California rose markedly in the decade since doctors stopped ...

Since 2019, the Hawks and PCF have partnered together to combat prostate cancer and raise awareness about the disease. Last ...