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重大突破!解析核苷酸诱导转录终止因子 ρ 超寡聚化失活新机制 ...
为解决细菌转录终止因子 ρ 在休眠或应激时的调控机制问题,美国俄亥俄州立大学的研究人员开展核苷酸对 ρ 影响的研究。发现 ADP 和(p)ppGpp 诱导 ρ 形成无活性寡聚体。该成果为理解细菌转录调控和开发抗菌药提供新视角,值得一读。
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