The San Francisco 49ers are a gigantic mess. Nothing looks right on offense. Injuries have decimated both sides of the ball.

ET on Sunday, the Chicago Bears play at the San Francisco 49ers.In their last outing, the 49ers lost 35-10 to the Buffalo ...

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and ...

Before the 2024 NFL season, Sunday night's Week 13 matchup between the Buffalo Bills and San Francisco 49ers might've been ...

San Francisco 49ers running back Christian McCaffrey was placed on injured reserve for the second time this season after ...

Should Guerendo start as expected Sunday, it will be just his second start as a running back since he was in the fourth grade ...

The tragedy of this 49ers’ season epitomized. For the first time since returning to the lineup in Week 10, McCaffrey looked ...

Buffalo Bills quarterback Josh Allen's third quarter touchdown was his second passing touchdown - and first receiving ...

Josh Allen isn't one to quit on a play. That was rarely clearer than in Sunday night's win over the San Francisco 49ers, when ...

The Bills and 49ers play Sunday, Dec. 1 at 8:20 p.m. at Highmark Stadium in Orchard Park. The game will be broadcast on local ...

Amid freezing temperatures and several inches of blanketing the field at Highmark Stadium, viewers enjoyed the full " Josh ...