To date, hundreds of AAV serotypes have been isolated from nature or synthetically designed in the lab, each with a unique physical capsid structure and biological attributes. AAV6, for example ...

AAV is a single-stranded DNA parvovirus that can be engineered to infect cells after 96% of the AAV genome has been replaced ... mutations in their capsid structure. After screening an initial ...

In 2014, researchers combined DNA barcoding with next-generation sequencing (NGS) to develop the adeno-associated virus (AAV) barcode-seq technology for streamlining ...

Mammoth Biosciences researchers have developed NanoCas, an ultracompact CRISPR nuclease, demonstrating its ability to perform ...

Gator Bio is the market’s sole solutions supplier that provides assays for genome titer and integrity, capsid titer, and empty-full ratio on a single automated platform. The AAV genome titer and ...

As they report, optimizing SXC conditions using isocratic separation to separate empty and full AAV capsids from the lysate enabled 51.7 percent of the viral genome to be recovered. It reduced DNA ...