“The tropism of natural AAV serotypes is limited,” he says. “They also tend to infect the liver, which can cause severe side effects in some cases.” Improving AAV tropism could offer ...

In fact, a variety of AAV serotypes can be used to achieve different tissue tropism, efficacy and drug delivery effects. Due to their diversity, and the need to remove process-related impurities, the ...

The kit is developed to be serotype-specific, covering types 2, 5, 8, and 9, which are common in AAV therapies. This ...