In contrast to ATP8B1 and ABCB11 diseases, ABCB4-deficient patients manifest high serum gamma-glutamyl transpeptidase (GGT) level, ductular proliferation, and inflammatory infiltration of the ...

Pol Boudes, M.D., Chief Medical Officer of Rectify, added “We believe our differentiated dual-targeted approach of addressing ABCB4 and BSEP ... a bile duct cancer, compared to the general ...

RTY-694 is a potent, orally active ABCB4/BSEP positive functional modulator ... rate of developing cholangiocarcinoma, a bile duct cancer, compared to the general population.