The crystal structure of a second G protein–coupled receptor sheds light on these key pharmaceutical targets. In contrast, β2AR and essentially all of the other GPCRs are present at very low ...

An early study with chimeric receptors between the alpha2c-adrenergic receptor and m3-muscarinic receptor suggested the possible heterodimerization between GPCR types. Direct evidence for GPCR ...

Advances in molecular genetics have identified genetic polymorphisms in the human ß-adrenergic receptor genes; some of this variation predicts changes in protein sequence/structure, and ...

The specificity of the immune response is determined by the unique epitopes recognized by individual antibodies and T cell receptors. The strength of the antibody-antigen interaction is determined by ...

No individual antipsychotic was associated with better cognitive outcomes than placebo in patients with schizophrenia spectrum disorders (SSD), according to a systematic review an ...

Abstract and Introduction Rationale for i.v. Antihypertensive Selection Clinical Pharmacology of i.v. Antihypertensives References There are potential concerns with the use of sodium nitroprusside ...

When breast cancer cells test positive for estrogen receptors, it’s called estrogen receptor-positive (ER-positive) breast cancer. It means that estrogen is fueling the growth of the cancer.

These receive incoming impulses from other neurones. Information from receptors passes along neurones, as electrical impulses to co-ordinators such as the central nervous system or CNS.

Gift 5 articles to anyone you choose each month when you subscribe. Pathology giant Healius, capitalised at $1.17 billion, has agreed to sell its Lumus radiology business to pan-Asian buyout group ...