综上所述，香菇多糖在体外和体内均表现出对Aβ和α-syn纤维聚集的抑制作用，并能够显著缓解其引起的神经毒性和行为缺陷。这些结果表明，香菇多糖可能作为一种潜在的治疗药物用于AD和PD的防治，这一研究为天然多糖类物质在神经退行性疾病中的应用提供了新的思路 ...

Figure 1: Imaging of amyloid-β deposits in the live mouse. Figure 3: In vivo imaging of amyloid-β deposits in 20-month-old homozygous PDAPP mice. Immunostaining with biotinylated or ...

Nearly 80 years would pass before the key components of these abnormalities were identified — beginning with the amyloid-β peptide in 1984. In the 1960s, electron microscopy and X-ray ...

By Dr. Liji Thomas, MD New study reveals how microalgae extracts and phytoene combat aging, protect against Alzheimer’s ...

Shimadzu Corporation, Eisai Co., Ltd., Oita University, and Usuki City Medical Association have demonstrated the utility of blood biomarkers in predicting the accumulation of amyloid beta (Aβ)(1) in ...

Two of the groups reported that cultured human oligodendrocytes make as much or more Aβ than do neurons, and that ...

Share on Pinterest New research looks into the role of amyloid-beta in developing Alzheimer’s. Westend61/Getty Images A main theory behind the cause of Alzheimer’s disease is the build-up of ...

近日，罗氏诊断阿尔茨海默病脑脊液系列试剂盒（包括Elecsys ® β-Amyloid (1-42) CSF II、Elecsys ® Phospho-Tau (181P) CSF、Elecsys ® Total-Tau CSF检测试剂，以及 ...

elegans and Protect against Amyloid-β Toxicity in an Alzheimer's Disease Model, Antioxidants (2024). DOI: 10.3390/antiox13080931 ...

Mild depressive symptoms in the preclinical stages of Alzheimer disease may be predictive of greater longitudinal amyloid burden.