14 , Jaenisch lab postdoc Punam Bisht and colleagues have uncovered an antiviral mechanism in bat cells that allows viruses ...

当RNA病毒感染时，信号转接器MAVS会在线粒体外膜上形成功能性的聚集体，作为连接病毒与下游抗病毒天然免疫反应的中心枢纽。目前已有多种调节MAVS激活的机制，但控制MAVS聚集的检查点尚未被发现。

Adding to the ever-growing list of newly discovered bacterial immune systems, we have characterized the mechanisms of an ...

4′-Fluorouridine works against RNA-dependent RNA polymerase, an enzyme that helps viruses assemble RNA. The compound has a ...

Key steps in the life cycle of HCV include entry into the host cell, uncoating of the viral genome, translation of viral proteins, viral genome replication, and the assembly and release of virions.

Additionally, the antiviral efficacy of vandetanib against COVID-19 variants such as alpha, beta, delta, and omicron was ...

McGill University scientists have discovered that pregnancy may trigger a natural immunity to boost protection against severe ...

On the other hand, mRNA of selenoprotein P binds to the regulatory domain (RD) of RIG-I, inhibiting production of type I interferon (IFN-β) that has antiviral activity. As a result, viral ...