Thirty years after the sequencing of the BRCA1 cancer-associated gene, access to genetic tests and awareness about its risks ...

New research shows that young breast cancer patients with high-risk genes may be able to prevent their cancer from returning ...

新研究表明在HER2阳性乳腺癌患者中，胚系BRCA1/2突变的发生率为6.6%，且不影响生存结果。乳腺癌是女性最常见的恶性肿瘤，遗传易感性作为其主要风险因素，在全部乳腺癌病例中占比达5%-10%。其中，约50%的病例与乳腺癌相关基因BRCA1和BRC ...

BRCA1 (breast cancer 1, early onset) is a tumor suppressor that probably has a DNA repair function. BRCA1 is expressed at high levels in the T cell lineage, however its function during thymocyte ...

Pharmacogenomics. 2012;13(13):1523-1535. 5-year survival for stage III and IV (%): carriers, 38.1; noncarriers, 24.5 Median survival: p = 0.002 5-year survival for stage III and IV: p < 0.001 [46 ...

One year of treatment with the targeted drug olaparib improves long-term survival in women with high-risk, early-stage breast ...

Such treatments could give people with BRCA1 mutations new options for cancer prevention, which are sorely needed. Right now, ...

Pharmacogenomics. 2012;13(13):1523-1535. 5-year survival for stage III and IV (%): carriers, 38.1; noncarriers, 24.5 Median survival: p = 0.002 5-year survival for stage III and IV: p < 0.001 [46 ...

That's because she has a gene mutation called BRCA1, which affects around one in every 300-400 people. This is her story in her own words. Hayley Minn Hayley's grandmother died of breast cancer ...

Genetic mutations can increase cancer risk. BRCA, Lynch syndrome, and TP53 mutations are linked to specific cancers. Regular ...