Hepatitis B virus (HBV) infection is a leading cause of chronic liver diseases that spreads among individuals through blood ...

Cryo-electron microscopy reveals the structural basis for the restriction of hepatitis B virus (HBV) entry in macaques, ...

A study reveals why monkeys resist HBV infection, showing that specific amino acid differences in their NTCP receptor prevent ...

An infection with the hepatitis B virus (HBV), which is spread by blood or bodily fluids, is one of the main causes of ...

As well as having a role in lipid absorption, bile acids can act as endocrine-signaling molecules. With previous studies suggesting that bile acids operate as metabolic integrators, Watanabe et al.

Prof. Watashi adds, "These animals probably evolved to acquire escape mechanisms from HBV infections without altering their bile acid transport capacity. Consistently, phylogenetic analysis showed ...

Odevixibat is a once-daily non-systemic ileal bile acid transport (IBAT) inhibitor approved under the brand name Bylvay ® in the U.S. as the first drug treatment option for patients 3 months of ...

Hepatitis B virus (HBV) has a narrow host range, mainly infecting hominoids. A new study reveals the structural differences in the liver cell receptor (NTCP) between humans and monkeys, explaining why ...

Prof. Watashi adds, “These animals probably evolved to acquire escape mechanisms from HBV infections without altering their bile acid transport capacity. Consistently, phylogenetic analysis ...