In hepatocytes, bile acids are secreted into bile canaliculi by bile salt export pump (BSEP), cholesterol is secreted by ATP binding cassette subfamily G member 5 (ABCG5) and ABCG8 heterodimer and ...

Liver needle biopsy of the patient showed severe cholestasis with bile casts in the canaliculi (Fig. 1). There was mild proliferation of bile ductules, which was accompanied by polymorphonuclear ...