A bitter taste receptor, TAS2R14, has been shown to respond to both extracellular and intracellular signals. Indeed, it can respond to both signals simultaneously. This finding is especially ...

This discovery is fascinating because bitter taste receptors are expressed in extra-oral tissues and the new study shows the potential of our cells to sense not only external but also internal ...

Using an established cellular test system, the Leibniz team discovered that five of the approximately 25 human bitter taste ...

But no one really knew why. It turns out that saccharin doesn’t just activate sweet taste receptors, it also blocks bitter ones — the same bitter taste receptors that cyclamate activates.

“Some may have a strong response to one bitter receptor ... and found that the inhibitor only blocks taste, not any other sensations in the mouth, like temperature, or even the tingling ...