CD4/MHC Class II, CD8/MHC Class I). Pathogenic Steps Inhibited by Efalizumab: (a) T-cell activation by antigen in the lymph nodes, (b) T-cell binding to the endothelium with migration into the ...
CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...