在免疫学中,标记分子是用于识别和分类不同免疫细胞类型的重要工具。尽管有些分子的名称相似,但它们在结构和功能上有细微差别。下面我们将详细解析常见标记分子及其差异,帮助你更好地理解它们在免疫系统中的作用。
免疫学家称它们为CD4+CD8+或“双阳性”细胞。重要的是,CD4共受体只会“夹在”类II MHC分子上,CD8共受体只会与类I MHC分子匹配。因此,CD4和CD8共受体 ...
CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...
At present there is no broad consensus on whether the apparent 'preoccupation' of the TCR repertoire with MHC molecules is due to the coligation of CD4 or CD8 coreceptors and the TCR by MHC ...
CD4+ and CD8+ T cells accumulate in the skin of patients with psoriasis. These cells are also identified by markers of activation (e.g., increased IL-2 receptors and HLA-DR surface molecules) and ...