This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...

How many naive T cells that are specific for any one peptide–MHC complex exist in an individual? How does that number influence the immune response? Answers to these questions have remained ...

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

Researchers have identified key immunological markers associated with mortality in hospitalised people living with HIV/AIDS.