*仅供医学专业人士阅读参考把肿瘤微环境内因抗原慢性刺激转入耗竭状态的CD8+T细胞“叫醒”，让它们重新活化为效应CD8+T细胞，是PD-1/L1抑制剂为代表的现有免疫治疗起效的关键，但实话实说，激活处在耗竭状态的CD8+T细胞，在奇点糕眼里总觉得有点 ...

2024年10月1日，温州医科大学附属第一医院陈钢团队在期刊《Gut Microbes》上发表了题为“Synergistic activity of Enterococcus Faecium-induced ferroptosis via ...

A study involving identical twins suggests alterations in immune cells called CD8 T-cells may be early drivers of ...

Here, researchers began by examining gene activity in cancer-fighting T cells ... which can serve as a long-term source of cytotoxic CD8+ T cells. This enzyme had also been identified in prior ...

They found that Fc–IL-4 improved the function and metabolic activity of terminally exhausted CD8+ T cells in tumors, leading ...

The researchers then systematically blocked the activity of individual metabolic ... of more mature tumor-fighters called cytotoxic CD8 + T cells. This enzyme had also been identified in prior ...

New non-human primate data show highly selective in vivo delivery of mRNA to T cells with a cell-targeted lipid nanoparticle ...

Equillium Inc. (Nasdaq: EQ), a clinical-stage biotechnology company leveraging a deep understanding of immunobiology to develop novel therapeutics to ...

A second CAR T-cell expansion started day on 39 but consisted of multiple CAR+ populations. Two CAR+ populations were characterized by CD4+ or CD8+ expression, and one population was negative for ...