liver sinusoidal endothelial cells (LSECs) are highly adept at taking up soluble antigens from the blood and cross-presenting these antigens on MHC class I molecules to passing naive CD8 + T cells.

CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...

Data from the ongoing Phase 2 of EO4010 demonstrate tumor target specific immune responses and objective tumor responses, including in liver ...