CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...
The CD8-mediated binding can usually be blocked by inclusion of select CD8 monoclonal ... Prepare 2x staining cocktail containing all of your labeled reagents at the right titer. The suggested titer ...
Tetramers and/or their derivatives are provided for research purposes only. Containing mutations in the MHC α3 domain that ablate CD8 binding; can be used to quantitate and to sort CD8-independent T ...