CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...
The CD8-mediated binding can usually be blocked by inclusion of ... Prepare 2x staining cocktail containing all of your labeled reagents at the right titer. The suggested titer for the MHC tetramer ...
Memorial Sloan Kettering Cancer Center researchers have found RNA neoantigen vaccines that generate long-lived, functional ...
Following allorecognition, CD4 + and CD8 + T cells become activated ... the direct pathway (intact donor MHC molecules displayed on donor antigen-presenting cells [APCs]) and the indirect pathway ...
Recipient T cells recognize donor antigens via two distinct pathways: the direct pathway (intact donor MHC molecules displayed on donor antigen-presenting cells [APCs]) and the indirect pathway ...