Its mechanism of action involves competing with CD28 to bind to CD80/CD86. CD28 is required for the full activation of T cells through binding of CD80/86 on the antigen-presenting cell ...
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New strategy for safer CAR T cell therapy in lymphomasThe research team found an increasing number of the surface proteins CD80 and CD86 in the tumor cells. Such a high number of these proteins is not found in healthy B lymphocytes (B cells), the ...
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