Cystic fibrosis is caused by faults in a gene called CFTR, which gives the body “instructions” to produce a protein that ...

The firm's chief scientific officer called the achievement "a major milestone for Spirovant and for the cystic fibrosis ...

ReCode Therapeutics is set to secure up to $15m in additional funding from the Cystic Fibrosis Foundation to enhance its gene ...

In the 1980s, the discovery of the CFTR gene and mutations that cause CF further solidified the role of the sweat test in ...

Take cystic fibrosis. It’s caused by a defect in the CFTR gene. But you need two copies of the defective gene to actually get the disease. So, if you only have one defective copy, you’re ...

The Gene Expression Core was founded in 1994 and promotes translational, multidisciplinary CF research by furnishing expertise concerning recombinant CFTR and other proteins relevant to CF disease ...

For example, cystic fibrosis is typically characterized as a single-gene disease associated with recessive mutations in the CFTR gene. However, more extensive studies of CFTR mutations in larger ...

in addition to maintenance of wild-type Sprague Dawley strain for additional use Generation and procurement of novel relevant CF animal models to understand newly developed CFTR modulators, and to ...

The CFTR gene was identified in 1989, but few companies jumped at the chance to use the information to develop new therapies, because the market was perceived as too small. It is therefore ...

Other rare mutations that are not eligible for CFTR modulators will be explored as the editing technology matures. “Gene editing is a promising, complex technology, which will take many years to ...

CF is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. An estimated 105,000 people have been diagnosed with CF across 94 countries, according to the CF ...