We applied a strategy of serial screening steps to 45 patients with congenital absence of the vas deferens and characterized cystic fibrosis transmembrane conductance regulator gene mutations in ...

The CFTR gene was identified in 1989, but few companies jumped at the chance to use the information to develop new therapies, because the market was perceived as too small. It is therefore ...

View Full Profile. Learn about our Editorial Policies. In their 2019 paper, Liu’s team used prime editing to alter the gene mutations causing sickle cell disease and Tay-Sachs disease. Liu explained ...

This discovery, along with the identification of other nitrogenous bases, laid the foundation for our ... A single C-to-T mutation in the beta-globin gene leads to the production of abnormal ...