The CFTR Protein Distribution Core offers high-quality, full-length recombinant cystic fibrosis transmembrane conductance regulator (CFTR) proteins expressed in and purified from mammalian cells. Wild ...
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Cystic Fibrosis Alters the Immune System From ChildhoodA study led by TUM researchers finds that cystic fibrosis alters immune cells early in life, likely before birth. These immature immune cells fail to fight infections, fueling persistent inflammation ...
The patient’s cells must produce the CFTR protein for the existing therapies to work ... selective organ targeting lipid nanoparticles (SORT LNP). 4 By modifying the composition and biophysical ...
The three key functions of the Core are listed below: These CF mouse models produce no functional Cftr mRNA or protein, and are particularly useful to stufy consequences of the electrophysiological ...
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