or other proteins known to influence CFTR function. The Core maintains a repository of over 50 constructs containing CFTR and other relevant mutations, together with gene editing and other molecular ...
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The long breath: Medical advancements giving cystic fibrosis patients a fuller lifePeople with CF typically have higher chloride levels in their sweat due to a malfunctioning CFTR protein, which affects the ...
It is being investigated in combination with the chemotherapy molecule called doxorubicin ... gene that allows lung cells to make a working CFTR protein and prevention infection.
Interaction of nascent secretory proteins in the ER with molecular chaperones ... protein (the cystic-fibrosis transmembrane conductor, CFTR). Activity of the lumenal Hsp70-like chaperone ...
Since 2012, he has served as director of the Center for Stem Cell and Regenerative Medicine (CSCRM) at the Brown Foundation Institute of Molecular Medicine ... patients with CF who produce ...
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