Because DCP-001 cells are derived from a cancer cell type they express multiple tumor-associated antigens, but with a mature dendritic cell phenotype. These antigens have been shown to overlap ...

On one hand, cancer cells need to lose their chemoprotective ... and a network of genes has been identified that confers a drug resistance phenotype similar to that of mammalian cells 9.

Malignant cells down-regulate cell death by overexpressing a transcription factor called BCL6. “Our idea was to borrow a little bit of the activity of the kinase and drag it over to where BCL6 is ...

奥希替尼是一种三代表皮生长因子（Epidermal Growth Factor Receptor, EGFR）酪氨酸激酶抑制剂（Tyrosine Kinase Inhibitor, TKI），目前是携带 EGFR ...

We draw from fundamental mechanisms of cell and tissue development and homeostasis, animal models of disease, and clinical samples in order to enhance our understanding of the biological processes ...

Breast cancer cells, when disseminated to other secondary organs such as the lungs, may stay in a dormant state for years, even decades. But the mechanisms that limit their expansion are not well ...

Some of the most widely used drugs today, including penicillin, were discovered through a process called phenotypic screening ...

We found that splice isoform switching of the CD44 gene must take place in order for cells to undergo EMT. We also discovered a novel splicing-mediated pathway that drives cancer metastasis. We ...

Neuroscientists have uncovered a mechanism that controls the reactivation of neural stem cells, which are crucial for ...

【第2集】BBC.The.Cell- 细胞 - 科普类型纪录片(1)（中） 译 BBC.The.Cell- 细胞 - 科普类型纪录片 - BBC.The.Cell- 细胞 - 科普类型纪录片(1)（中） ...

The work presented will be of interest to cancer biologists and more broadly to those interested in NSCLC translational studies. Non-small cell lung cancer (NSCLC) is the most common subtype of lung ...

Program for Cancer and Cell Biology, Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences; Peking University International Cancer Institute; and State Key Laboratory ...