NK cells recognize cell-bound antibodies via CD16A (FcγRIIIA) to mediate antibody-dependent cellular cytotoxicity (ADCC). Potentiating therapeutic mAb-mediated CD16 activation of NK cells is an ...

in which CAR-NK cells can kill target cancer cells independently via CAR and also serve as CD16-positive effector cells for mitigating ADCC against cancer cells. Sino Biological has created a ...