Figure 2: Cell death and viability assay in cultured cells expressing various APP and CTF constructs. Having established that APP can be cleaved by caspase-8 and caspase-9 in cultured cells and ...

For example, researchers will measure cell death to determine a drug’s anticancer effectiveness. Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark ...

Cell Death Assays. We performed TUNEL assay with the apoptosis detection system, Fluorescein (Promega) according to the manufacturer's protocol. Transfected cells were treated with STI571 alone ...

In Ming-Chiu Fung’s immunology lab, Hogan had been investigating how disturbances in the cytoskeletons of cells might contribute to the fragmentation of mitochondria during apoptosis, the most ...

He noted that other assays studied in pancreatic cancer have only examined a handful of samples. "When they publish a second paper, it usually shows that [the test] fails for earl ...

Developed using the Acrivon Predictive Precision Proteomics (AP3) platform, the multiplex immunofluorescence assay is currently ... driving pro-apoptotic cell death. The FDA's breakthrough device ...