This evidence implicates TRPM2 in a broad range of pathways that take place every stage of cerebral ischemic injury, thus making TRPM2 a promising target for drug development for stroke and other ...

The study, published in The Journal of Pathology, which is based on ... may pave the way for new treatments that help the brain repair itself. A stroke occurs when the blood supply to part of ...

A new study by researchers at the Department of Molecular Medicine at SDU sheds light on one of the most severe consequences of stroke: damage to the brain's "cables"—the so-called nerve fibers ...

In hemorrhagic stroke, underlying vascular pathology might be a contributory factor, although a role for pre-existing vascular pathology as a risk factor for stroke related to drug use has not ...

1 Vascular Immunology Unit, Department of Pathology, Sydney Medical School, The University of Sydney, Camperdown NSW 2042, Australia. Cerebral malaria (CM) is a complex of syndromes relating to ...

Despite upstream recanalization in acute ischemic stroke, it is now increasingly recognized that blood flow may fail to reach downstream tissue ...

Necroptosis is the predominant form of neuronal death after ischemic stroke. This study identifies the deubiquitinating enzyme OTUB2 as a novel regulator of the RIPK1-RIPK3-MLKL necroptotic signaling ...

The effects of hyperglycemia on the injured brain have been studied in both animals and humans. Hyperglycemia has been associated with increased cerebral lactate resulting in local brain tissue ...

The department of neuromusculoskeletal medicine at Vietnam-Sweden Uong Bi Hospital in Quang Ninh Province, northern Vietnam ...