早在 2022 年，李劲松研究组报道了利用类精子干细胞介导半克隆技术，通过 CRISPR/Cas9 靶向染色体重复序列实现小鼠染色体融合改造，建立全新的稳定传递的染色体改造纯和小鼠品系，揭示了染色体融合的机制，并提示真核生物基因组组装的系统稳健性（ Robustness ...

In this week's PEOPLE cover story, Denise Richards opens up about her daughter Eloise, and the blessings and challenges she's ...

Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro ...

This method is most useful for examining chromosomal translocations, especially ones involving the Y chromosome. Taken together, these banding techniques offer clinical cytogeneticists an arsenal ...

BGI Genomics' Indonesian joint venture NGI signed a partnership agreement for research collaboration with  Indonesian ...

Testosterone treatment significantly reduces mortality among men with Klinefelter syndrome. Researcher calls for changes in guidelines to ensure more patients receive the necessary treatment.

By Balambal Suryanarayanan CRISPR-Cas9 is a repurposed gene editing tool that allows scientists to cut, replace, and insert pieces of DNA in precise regions along the strand. Courtesy of NIH Image ...

The phenomenon that produces such genomic chaos is known as chromosomal instability (CIN). Cancer researchers and clinicians have long appreciated CIN as a hallmark of advanced and metastatic cancers; ...