Common ototoxic drugs (drugs that can have toxic effects on the ears) include antibiotics, analgesics (pain relievers), blood pressure medications, anticonvulsants (anti-seizure drugs), and others.

The aminoglycoside antibiotics (amikacin ... nephrotoxicity is trough-dependent (predose levels). Vestibular and ototoxicity are less well correlated with levels and are thought to be related ...