GPCRs such as the β2ARs also undergo regulated endocytosis that is mediated by agonist concentration in pre-existing clathrin-coated pits 111. β2ARs were found to concentrate uniformly in ...

Using microscopy and biochemical studies, they concluded that SFV was entering cells by using the clathrin-mediated endocytosis pathway. Helenius's work linked the story of viruses to the story of ...

One key process in maintaining this equilibrium is endocytosis, the mechanism by which membrane components are internalised. Organisms have evolved various endocytic pathways, all relying on ...

Some larger cargo, such as membrane proteins, nutrients, and pathogens, enter the cell via a process known as clathrin-mediated endocytosis. To gain a deeper understanding of this important ...

Wan, C., Puscher, H., Ouyang, Y., Wu, J., Tian, Y., Li, S., Yin, Q., Shen, J. (2024) An AAGAB-to-CCDC32 handover mechanism controls the assembly of the AP2 adaptor ...

Bridging integrator 1 (BIN1) is a widely expressed adaptor protein that is part of the Bin1/amphiphysin/RVS167 (BAR) family. BIN1 functions in clathrin-mediated endocytosis and endocytic recycling, as ...