Using microscopy and biochemical studies, they concluded that SFV was entering cells by using the clathrin-mediated endocytosis pathway. Helenius's work linked the story of viruses to the story of ...

Some larger cargo, such as membrane proteins, nutrients, and pathogens, enter the cell via a process known as clathrin-mediated endocytosis. To gain a deeper understanding of this important ...

GPCRs such as the β2ARs also undergo regulated endocytosis that is mediated by agonist concentration in pre-existing clathrin-coated pits 111. β2ARs were found to concentrate uniformly in ...

In our lab, we focus on clathrin-mediated endocytosis, the predominant route for membrane internalisation in most cells. In addition to its role in endocytosis, the clathrin machinery also forms ...