Results: The pharmacokinetics of intravenous fentanyl reflected a 2-compartment model with a clearance of approximately 1.5 L/min. There was moderate (< 50%) between-subject variability (BSV ...

The pharmacokinetics of fentanyl by the intravenous route can be described by a 2-compartment model in this patient group, and using this study design. The clearance of fentanyl was approximately ...