该研究开发了一种基于CRISPR-Cas13的靶向RNA的转录组规模的CRISPR筛选技术，并使用该技术在来自不同组织的5种人类细胞中筛选鉴定了778个必需的lncRNA。

thus effectively establishing a paradigm for next-generation CRISPR screens. The approach has broad applications in identifying novel drug targets or elucidating unknown mechanisms of actions of ...

The ultimate goal, he says, is to make CRISPR safer and more reliable. By refining its use, the team hopes to expand its applications to include tissue regeneration and increasing the therapeutic ...

Researchers in Lithuania present the molecular structure of a new, more-versatile CRISPR system for gene editing.

CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell.

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...

In recent years, scientists have created a range of new methods based on CRISPR-Cas technology for precisely editing the genetic material of living organisms. One application is in cell therapy ...

The genome-editing technology can be supercharged by artificial intelligence—and the results are already being felt.

Subsequently, they highlighted recent developments on the therapeutic applications of probiotics that were genetically ...

Nov. 6, 2024 — The CRISPR tool is capable of repairing the genetic defect responsible for the immune disease chronic granulomatous disease. However, researchers have now shown that there is a ...