Cryopyrin-associated periodic syndromes (CAPS) are a family of related conditions associated with heterozygous mutations in NLRP3 (formerly CIAS1), the gene that encodes the NACHT, LRR and PYD ...
On February 27, 2008, the Tarrytown, New York-based Regeneron Pharmaceuticals received approval for Arcalyst (rilonacept), a treatment for cryopyrin-associated periodic syndromes (CAPS), including ...
Ilaris was approved by the FDA in 2009 to treat two subtypes of a rare autoinflammatory disease called Cryopyrin-Associated Periodic Syndromes (CAPS): Muckle-Wells syndrome (MWS) and Familial Cold ...