A study from the Cleveland Clinic reports standardized results of the TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labeling) assay for the assessment of sperm DNA damage. This assay ...
The genetic connections between DNA repair pathways and human cancer predisposition have fueled interest in the proteins that recognize and repair specific sites of DNA damage. The repair enzymes are ...
There is significant crosstalk between DNA damage response (DDR ... The Transcreener HTS Assay platform helps to accelerate these efforts by providing a reliable and user-friendly biochemical ...
The study demonstrates how these proteins collaborate in so-called "hubs" to repair DNA damage. This knowledge offers opportunities to improve cancer therapies and other treatments where DNA ...
The study delves into the role of BEND4 in DNA damage repair and its potential ... including cell line experiments, tissue sample analysis, and in vivo studies. The researchers evaluated the ...