New research provides evidence that synaptic NMDAR number and subunit composition are not static, but change dynamically in a cell- and synapse-specific ... and long-term depression (LTD ...

Two major forms of synaptic plasticity, long-term potentiation (LTP) and long-term depression (LTD ... both LTP and LTD can occur at the same synapse in response to different patterns of ...

Researchers from Bonn and Japan have found that the sharing of proteins and calcium makes synaptic plasticity a collective ...

We are particularly interested in the phenomena of long-term potentiation (LTP) and long-term depression (LTD), which are forms of synaptic plasticity exhibited by many different classes of synapse in ...

If so, their precision of plasticity is high. The Salk team applied concepts from information theory to analyze synapse pairs from a rat hippocampus—a part of the brain involved in learning and ...

Insulin-like growth factors (IGF1/IGF2-cyan spheres) are released from the postsynaptic compartment of a synapse during plasticity. To understand how IGF1 and IGF2 promote memory formation ...

In addition, while the plasticity was happening at a specific synapse, CaMKII was active in a much larger area of the neuron. The research revealed that CaMKII is an instructive signal for BTSP ...

Until now, it was assumed that each synapse decides independently of the others how it changes A recent study suggests a new perspective on how neighboring synapses coordinate their response to ...