This may hint at what lies ahead as we navigate the (mostly erroneous) tendency to identify every cell death process in drug ...

DILI is broadly categorized into intrinsic and idiosyncratic types. Intrinsic hepatotoxins, such as APAP, cause ...

推荐意见1：明确危险因素可以预防和早期发现ATB-DILI。NAT2慢乙酰化基因型和GSTM1基因变异、高龄、肝炎病毒感染或合并其他急慢性肝病、HIV感染、营养不良和酒精（乙醇）摄入是ATB-DILI的危险因素（2，B）。

Drug-induced liver injury (DILI) can present as a chronic phenotype or acute course. However, there is a lack of research on ...

Drug-induced liver injury (DILI) is common because it can be caused by different pharmacological agents from nearly all classes of medications, including hepatotoxic drugs, anesthetics, anticancer ...

Derisking of drug-induced liver injury (DILI) continues to be a challenge for pharmaceutical scientists. Join Michael Hafey, Principal Scientist at Merck, as he discusses how to utilize a two-tiered ...

and ASO to determine the risk of DILI in humans. At least six hepatic health parameters, including clinical indicators of liver injury, are simultaneously assessed by the service. This method ...

Recent draft guidance highlights the challenges that industry and regulators face to predict rare drug-induced liver injury. At the end of August 2008, the consultation period ended for comments ...

Drug-induced liver injury including cholestasis is another form of acquired liver disease, accounting for approximately 2 to 5% of hospitalizations for jaundice, 10% of cases of hepatitis in all ...