In 1974 Creighton 27 used the coupling between folding and disulfide bond formation to isolate covalently trapped disulfide intermediates in the refolding/reoxidation of bovine pancreatic trypsin ...
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER), as reported by researchers at Science Tokyo.
In eukaryotic cells—found in animals, plants, and fungi—protein synthesis involves more than the simple assembly of amino acids in ribosomes. Nearly ...