Cystine contains reactive disulfide bonds that can react with various proteins throughout the cell, with toxic effect. Cells use the reducing agent NADPH to neutralize cystine, and NAPDH is mainly ...
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER), as reported by researchers at Science Tokyo.
In eukaryotic cells—found in animals, plants, and fungi—protein synthesis involves more than the simple assembly of amino acids in ribosomes. Nearly ...