The NMR and Drug Metabolism Core has developed rapid and efficient approaches to investigate metabolism, metabolic stability, pharmacokinetics (PK), and chemical structure identification of small ...

Metabolism and individuality in drug response The need to understand individuality in drug response and associated benefits is a primary force behind the current industry trend toward the ...

The application of pharmacogenetics in identifying single nucleotide polymorphisms (SNPs) in DNA sequences that cause clinically significant alterations in drug-metabolizing enzyme activities is ...

The NMR and Drug Metabolism Core at Baylor College of Medicine offers tools to support the discovery, synthesis, screening, optimization, metabolism and pharmacokinetics of small molecule ligands or ...

ALDERLEY PARK, Cheshire - Infex Therapeutics Holdings plc, a UK-based anti-infectives specialist, in partnership with Justus-Liebig-University Giessen (JLU) in Germany, has been awarded a £1 million ...

The cell atlas, called Hypomap, developed by researchers at the Max Planck Institute for Metabolism Research in Cologne and the University of Cambridge, is being made available to the scientific ...

The team changed drug delivery tactics, starting with a high dose and tapering off—and stopping after four weeks. "This way, ...

These ‘GLP-1 agonists’ mimic a natural gut hormone — glucagon-like peptide 1 — to suppress appetite and regulate metabolism.

Despite such growth, there remains a set of complex hurdles associated with drug development for rare metabolic diseases. Inborn Errors of Metabolism Drug Development 2020 is dedicated to ...

Drug-induced liver injury (DILI ... as they discuss the current understanding of the mechanisms that contribute to DILI and how advances in reactive metabolism trapping have improved detection ...