Many drugs show “polypharmacology,” meaning they clearly affect distinct targets. These 'off-target' profiles can be very different despite similarities in chemical structure, which is not as ...
233,003 bottles of duloxetine have been recalled due to potentially containing high levels of cancer-causing impurities.
To be useful for drug discovery, a 3-D protein structure must be in sharp focus ... computing allow researchers to do a broad sweep of chemical space that was once impossible, Abel says.
A 22-year-old found dead in the front seat of his car had taken protonitazene pills, a drug “more powerful than fentanyl,” ...
All of these drugs act at the mu-opioid receptor ... much in the way that naloxone, which has a chemical structure very close to morphine, is an antagonist for morphine, heroin and oxycodone ...
FDA recently awarded new chemical entity (NCE ... versions of previously approved drugs, such as Austedo, the only difference in the molecule’s structure is at least one hydrogen atom has ...
Ingestion of doses as small as 0.25mg can be fatal," states the US Drug Enforcement Agency (DEA). Getty Images It's also relatively easy to alter its chemical structure to produce similar ...
FDA found the source of nitrosamines can be related to the drug’s manufacturing process or its chemical structure or even the ...