Many drugs show “polypharmacology,” meaning they clearly affect distinct targets. These 'off-target' profiles can be very different despite similarities in chemical structure, which is not as ...
Drugs are classified into different groups according to their chemical characteristics, structure and how they are used to treat specific disease. Medindia brings you the list of eighty six such ...
To be useful for drug discovery, a 3-D protein structure must be in sharp focus ... computing allow researchers to do a broad sweep of chemical space that was once impossible, Abel says.
All of these drugs act at the mu-opioid receptor ... much in the way that naloxone, which has a chemical structure very close to morphine, is an antagonist for morphine, heroin and oxycodone ...