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Unlocking mitochondrial secrets: New hope for Parkinson’s treatment
In an effort to restore mitochondrial function in Parkinson’s, we targeted a key protein that controls mitochondrial dynamics called dynamin-related protein 1, or Drp1. Naturally abundant in ...
Mitochondria keep your brain cells alive − helping them run smoothly may protect against Parkinson’s disease
In an effort to restore mitochondrial function in Parkinson’s, we targeted a key protein that controls mitochondrial dynamics ...
Nature1y
Pathways of clathrin-independent endocytosis
The mechanism of budding in the dynamin-independent pathways remains elusive; however, recent theoretical studies provide testable ideas in this area. There are numerous ways that endocytic cargo ...
Business Insider20d
Walden Biosciences Fully Enrolls First Cohort in Phase 2 Basket Study of WAL0921 in Chronic Kidney Diseases
Walden’s second most advanced program is an IND-ready small molecule that is designed to stabilize and restore the function of dynamin, an enzyme responsible for the maintenance of the cytoskeletal ...
Nature5y
Position of Drp1/Dnm1 protein on mitochondria.
Mitchondria are in a constant state of fusion and division inside the cell. Learn how this organelle is not just a passively floating ovoid structure.
Baylor College of Medicine9mon
Zhou Lab Publicatations
The nucleoside diphosphate kinase NDK-1/NME1 promotes phagocytosis in concert with DYN-1/Dynamin. FASEB J. 2019 Oct;33(10):11606-11614. doi: 10.1096/fj.201900220R. Epub 2019 Jul 17. PubMed PMID: ...