外泌体是细胞分泌的纳米级囊泡,它们在细胞间通讯中扮演着关键角色,并参与多种生理和病理过程。这些纳米级别的结构不仅能够携带蛋白质、脂质、以及核酸等生物分子,还能穿越生物屏障,如血脑屏障,为靶向药物递送和基因治疗提供了一个全新的平台。而工程化外泌体技术因 ...
【导读】小细胞外囊泡(sEVs)在各种生物学背景下是重要的细胞间信息传递者,但它们的释放过程仍然不为人所充分理解。在这项研究中,团队描述了一个高通量检测平台,CRISPR辅助的个体条形码sEVs释放调节因子(CIBER)筛选,用于识别sEVs释放的关 ...
Researchers at Germans Trias i Pujol Research Institute (IGTP) and Institut d'Investigació Sanitària Pere Virgili (IISPV) ...
Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole ...
Researchers at IGTP and IISPV have conducted a review on the therapeutic potential of extracellular vesicles in inflammatory bowel disease. While this approach remains in the early stages of research, ...
Bitter taste receptor has hidden intracellular pocket that enables activation via simultaneous extracellular/intracellular ...
大家好!今天来了解超分子水凝胶文章——《Using Chemistry To Recreate the Complexity of the Extracellular Matrix: Guidelines for Supramolecular Hydrogel–Cell Interactions》发表于《Journal of the American Chemical ...