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生物通
11 天
褐藻糖胶:开启非酒精性脂肪肝治疗新篇,调控关键通路对抗脂质 ...
在构建 NAFLD 球体模型后,研究人员发现,球体在培养过程中逐渐形成了正常肝细胞的形态。FFA 刺激会抑制球体活力,而褐藻糖胶处理后,球体活力明显恢复。同样,FFA 会使球体中 TG 含量升高,褐藻糖胶则能让它降下来,油红 O 染色也再次证实了褐藻糖胶可以抑制球体中的脂质积累。这些结果充分表明,褐藻糖胶就像一位 “减脂小能手”,能够有效改善 FFA 诱导的脂质积累问题。
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