【导读】脂质代谢紊乱是肝细胞癌（HCC）发生和发展的关键特征。癌细胞中异常表达的免疫球蛋白（Ig），尤其是具有独特Vκ4-1/Jκ3重排的Igκ轻链，与肿瘤的恶性程度增加有关，并与结肠癌的发生有关。然而，Igκ在HCC癌变中的作用尚不明确。10月9日 ...

中国高尿酸血症目前发病率约17.7%，患病人数已超过1.85亿，且呈明显上升和年轻化趋势；高尿酸血症已经成为继高血脂、高血糖与高血压后名副其实的“第四高”。高尿酸血症除了诱发痛风外，还是肥胖、糖尿病、心脑血管、高血压、肾病等多种常见代谢性疾病的独立危险因素。在全国高达2500万的痛风患者中，血脂异常率大约占一半以上；前期孟德尔随机分析提示高甘油三酯血症可能是高尿酸血症的诱因，但其潜在机制仍不清楚。

The findings are significant for the liver research community and others interested in the gut-liver axis. (A) AOAH cleaves the two piggyback fatty acyl chains from the lipid A moiety, inactivating ...

“早上困，中午困，下午困，晚上一拿手机就不困”“熬最长的夜，敷最贵的面膜”“三点睡五点起，阎王夸我好身体”......成了不少年轻人/打工人的真实写照。睡眠的重要性不言而喻，但随着社会飞速发展以及生活节奏加快，“拼命十三郎”们只能舍弃睡眠时间，转而投 ...

During beta-oxidation, fatty acid molecules are broken down by removing two-carbon units from the carboxyl end of a fatty acid molecule to produce acetyl-CoA.

A recent study suggests that a carbohydrate-rich breakfast for men and a fat-rich breakfast for women may be best for ...

Oil is a product we find in every kitchen, but are we truly sure how to store it correctly? It seems straightforward—we keep ...

Brown adipose tissue (BAT) facilitates thermogenesis through fatty acid oxidation (FAO). Paradoxically, BAT simultaneously increases anabolic fatty acid synthesis (FAS), the reason for which is ...

However, the frying process causes chemical changes in the food and oil. That's why using just any oil is not best. For ...

Experts say that certain nuts offer surprising advantages—including a lower risk of cancer, better cognitive function, and ...

The rumen microbiota—a symbiont to its host and consists of critical functional substances—plays a vital role in the animal ...