At the University of Illinois Comprehensive Sickle cell Center, 9,832 consecutive ... studied but found to be of no significance. High fetal hemoglobin in cord blood has been well described ...

All four sickle cell disease patients in the efficacy cohort had fetal hemoglobin levels above Beam’s target—and the result achieved by Vertex’s rival therapy—but one patient died ...

CRISPR is turned into a drug delivery system that helps recreate fetal hemoglobin, which then changes into red blood cells. Because the gene mutation for sickle cell disease is not found in fetal ...

Some scientists are especially “interested in doing research with fetal liver because it’s a rich source of stem cells,” which can have important therapeutic applications, says Dr.

Aruvant is developing ARU-1801 as a therapy designed to boost levels of functional fetal hemoglobin in β-thalassemia patients and restore normal red blood cell function. “At Aruvant ...

This oral medication is considered a first-line treatment for sickle cell disease, and can help reduce pain crises. Hydroxyurea causes the body to produce fetal hemoglobin, a type of hemoglobin ...

a cell therapy that includes the same therapeutic edit as BEAM-101 (editing the HBG1/2 genes to elevate fetal hemoglobin), plus an additional edit to CD117 which is designed to prevent binding of ...

5 news release from the company. Data from the phase 1/2 Beacon trial indicated that Beam-101, the company’s sickle cell therapy, increased fetal hemoglobin levels from an initial range of 4% to ...