Aruvant is developing ARU-1801 as a therapy designed to boost levels of functional fetal hemoglobin in β-thalassemia patients and restore normal red blood cell function. “At Aruvant ...

Though he doesn't remember it, Branden Baptiste had his first sickle cell crisis at age 2. Through elementary school, he was ...

CRISPR is turned into a drug delivery system that helps recreate fetal hemoglobin, which then changes into red blood cells. Because the gene mutation for sickle cell disease is not found in fetal ...

Beam’s CRISPR therapy for sickle cell yields consistent results with more patients In more sickle cell news, seven patients ...

Useful in establishing the differential diagnosis of anemia, calculated by automated blood profiling machine from RBC count, hematocrit and hemoglobin Red Cell Distribution Width (RDW) Expresses ...

Though he doesn't remember it, Branden Baptiste had his first sickle cell crisis at age 2. Through elementary school, he was ...

By birth, γ-globin production is normally switched off, but a significant fraction of RBCs still contain a mixture of fetal and adult hemoglobin. Because the sickle-cell mutation is present only ...

Beam Therapeutics (BEAM) announced new safety and efficacy data from its BEACON Phase 1/2 clinical trial of BEAM-101 in patients with sickle cell disease with severe vaso-occlusive crises ... editing ...

This oral medication is considered a first-line treatment for sickle cell disease, and can help reduce pain crises. Hydroxyurea causes the body to produce fetal hemoglobin, a type of hemoglobin ...

5 news release from the company. Data from the phase 1/2 Beacon trial indicated that Beam-101, the company’s sickle cell therapy, increased fetal hemoglobin levels from an initial range of 4% to ...

The hallmark symptom of sickle cell anemia is pain, particularly episodes of sudden pain, sometimes called sickle cell crises ...