Using advanced high-speed atomic force microscopy (HS-AFM), the team was able to observe Aβ fibril growth at the molecular level in real time. The work is published in the Journal of the American ...

Among these, several molecules, such as lysozyme, were shown to be involved in amyloid fibril formation. The findings were ...

Alanine substitutions in tau help identify distinct fibril folds. The technique pinpoints which residues are needed for each type of tau twist. It also tracks with neuropathological diagnoses, ...

Limitations of the three putative mechanisms of amyloid fibril assembly for explaining Sup35 prion formation have led to the introduction of a fourth model — nucleated conformational conversion ...